Calcium-D-Glucarate

SKU: CDG060

Product Size: 60 vegetarian capsules

Availability: In stock

Price: $31.50

Quick Overview

Calcium-D-Glucarate is calcium bound to d-glucaric acid, which is a natural compound produced in small amounts by the human body and is abundantly found in various plant foods such as broccoli, cabbage, kale, apples, oranges, and grapefruit.


Research shows that d-glucaric acid derivatives such as calcium-d-glucarate help support the body’s natural elimination of excess steroid hormones and toxins. Calcium-d-glucarate assists in the detoxification process as it forms conjugates with unwanted estrogenic hormones and environmental toxins, which are then eliminated from the body instead of being reabsorbed.

Calcium-D-Glucarate

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Mechanism of Action


In the GI tract, calcium-d-glucarate is metabolized into three compounds, the most active being D-glucaro-1,4-lactone. This metabolite increases the detoxification of carcinogens by inhibiting β-glucuronidase, an enzyme that can deconjugate potential toxins which are being eliminated via the phase II detoxification glucuronida¬tion pathway, allowing them to be reabsorbed back into the body instead of being excreted. With the inhibition of β-glucuronidase, toxins can be safely excreted from the body.


Glucaric acid is not available as a supplement, while calcium-d-glucarate is. Oral supplementation of calcium-d-glucarate is an ideal way to provide the body with an efficient, slow-release source of D-glucaro-1,4-lactone. By supplementing d-glucarates, in this case, the stabilized calcium form, one can favor the body’s natural defense mech¬anism for eliminating toxins, carcinogens and other tumor-promoting drugs, reducing their effects.

As a dietary supplement, take two capsules per day with meals, or as directed by your health care practitioner.
Serving Size: 2 capsules
Servings Per Container: 30
Does not contain gluten.

Color, size or shape may appear different between lots.